Hepaticįrequency not reported: Cholestatic jaundice, centrilobular necrosis, fulminant hepatic necrosis, death Patients with underlying congestive heart failure are predisposed to renal side effects associated with enalapril. The concomitant use of beta blockers with enalapril has been shown to be renoprotective.Įnalapril may worsen renal insufficiency, especially if the patient is hypovolemic or hypotensive. Enalapril reduced the risk of renal impairment compared to placebo in diabetic patients. Diuretic use and advanced age increase the risk of renal impairment. Uncommon (0.1% to 1%): Angioedema Nervous systemĬommon (1% to 10%): Vertigo, fatigue, peripheral paresthesias, insomnia, dizziness, syncope RenalĬommon (1% to 10%): Increased serum creatinine, uric acid, and potassium Įnalapril, like other angiotensin converting enzyme inhibitors, may decrease serum aldosterone levels, resulting in mild to moderate hyperkalemia. Predisposing risk factors for hypotension after enalapril (the active ingredient contained in Vasotec) administration are decreased intravascular volume (angiotensin-dependency), hyponatremia, and concurrent use of a diuretic agent. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.Ĭheck with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More commonĪpplies to enalapril: compounding powder, intravenous solution, oral liquid, oral tablet. These side effects may go away during treatment as your body adjusts to the medicine. Some side effects of enalapril may occur that usually do not need medical attention. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position.Although not all of these side effects may occur, if they do occur they may need medical attention.Ĭheck with your doctor immediately if any of the following side effects occur while taking enalapril: More common Serious side effects of VasotecĪlong with its needed effects, enalapril (the active ingredient contained in Vasotec) may cause some unwanted effects. Oral route (Tablet Solution Powder for Solution)ĭiscontinue enalapril maleate as soon as possible when pregnancy is detected, since fetal toxicity, including injury and death to the developing fetus, can be caused by drugs that act directly on the renin-angiotensin system.
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